Topical dht blockers?

*CherryPie*

Well-Known Member
Would dht products work on traction alopecia? My hairline is kind of thin from bunning in my teens and 20s. I need to thicken it up.
 

g.lo

Well-Known Member
Well I have what seems two different types of hair loss. I had a patch above my ear where I could physically see the DHT attached the the hair follicles and that patch stopped shedding about 3-4 weeks after using the freezing shampoo. It's now very slowly going back. I also have hair loss in the crown Area which so far hasn't grown back so I'm assuming it isn't DHT related hair loss. I don't really know what else do do about that. I have started using castor oil on it though.

I only used the freezing shampoo. I did get some scalp drops but didn't use it for long. I don't like them.


hi, could you please explain how you can see the bolded, just out of curiosity.
 

melissa-bee

Well-Known Member
hi, could you please explain how you can see the bolded, just out of curiosity.
It's the same colour as dandruff. I noticed that that each hair that shedded in that area there had this tube like build up wrapped around the whole stand on the root of my hair. After the hair strand came out, I could pull this tube like thing all the way down the strand of my hair. Even a couple of days after washing my hair I could see it there when the hair and follicle was still intact on my scalp and I could some times pull the build up down the strand of my hair. Because this build up seems to grow on and around the follicle I believe it is DHT because it seemed to be suffocating my follicle and make my hair shed a lot easier, which is said to happen when you go bald. I did some research on some baldness forum and saw some men witness the same thing.
 
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Beamodel

Well-Known Member
I thought DHT was a hormone. I didn't think it could be visible but I could be wrong.

Are you certain you didn't see the white bulb that comes out with all shed hairs?
 

g.lo

Well-Known Member
It's the same colour as dandruff. I noticed that that each hair that shedded in that area there had this tube like build up wrapped around the whole stand on the root of my hair. After the hair strand came out, I could pull this tube like thing all the way down the strand of my hair. Even a couple of days after washing my hair I could see it there when the hair and follicle was still intact on my scalp and I could some times pull the build up down the strand of my hair. Because this build up seems to grow on and around the follicle I believe it is DHT because it seemed to be suffocating my follicle and make my hair shed a lot easier. Which is said to happen when you go bald.
I did some research on some baldness forum and saw some men witness the same thing.


thank you for explaining this, the reason why I asked the question is I am studying trichology ( science of hair and scalp), and during on of my practical class, i asked if dht can be visible to human eye or microscope, and the teacher said no, you can't see due to the fact it is an hormone.
but what you are describing sounds very much like hair casts (could be wrong).
it look like a white speck on the hair and they can be slide up and down the hair. hope this help.
 

melissa-bee

Well-Known Member
I thought DHT was a hormone. I didn't think it could be visible but I could be wrong. Are you certain you didn't see the white bulb that comes out with all shed hairs?
Very certain it wasn't the bulb. When I fist joined this forum over 5 years ago I learned the difference between shed hair and breakage so then began a habit of studying my shed hairs for a while. So I am confident that I am aware of what a standard shed hair looks like. I was also able to slide this build up down and my hair would still be attached to the root. Also the DHT blocking shampoo did stop this build up in that area. Also another reason why I say this is because is suffer from mild to medium hirsutism. You may be aware that this creates additional hair growth in woman where men are more likely to have it. This is due to excess hormones called androgens. Also androgens create DHT which is why I am even more certain that the build up was DHT.
 
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g.lo

Well-Known Member
Very certain it wasn't the bulb. When I fist joined this forum over 5 years ago I learned the difference between shed hair and breakage so then began a habit of studying my shed hairs for a while. So I am confident that I am aware of what a standard shed hair looks like. I was also able to slide this build up down and my hair would still be attached to the root. Also the DHT blocking shampoo did stop this build up in that area.

Also another reason why I say this is because is suffer from mild to medium hirsutism. You may be aware that this creates additional hair grown in woman where men are more likely to have it. This is due to excess hormones called androgens. Also androgens create DHT which is why I am even more certain that the build up was DHT.



You are right DHT is the strongest androgen and can cause build up as well.
 
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melissa-bee

Well-Known Member
thank you for explaining this, the reason why I asked the question is I am studying trichology ( science of hair and scalp), and during on of my practical class, i asked if dht can be visible to human eye or microscope, and the teacher said no, you can't see due to the fact it is an hormone. but what you are describing sounds very much like hair casts (could be wrong). it look like a white speck on the hair and they can be slide up and down the hair. hope this help.

Thank you for the name that was very helpful. I just did a search on google images and what I was experiencing looked exactly like hair casts.
I did do a quick google search and I didn't find much information about it relating to hair loss. And I experienced a lot of hair loss in the area I saw these casts my hair, was the same length as the rest about 8 inches and it went down to less than a cm. hmm now I'm not so certain. I read that these casts can be caused by psychological trauma, I had been a bit stressed but I wouldn't call it trauma unless it was delayed by 2 years or more.
But even if they were just hair casts, I would say that the ingredients in the DHT blocking shampoo still played a part in getting rid of them.
 

melissa-bee

Well-Known Member
Before I tried the DHT blocking shampoo I tried and a finished a shampoo given to me buy my doctor, which contained ketoconazole. I also tried t/gel and that didn't help.
 

sugarbaybie

Well-Known Member
(I hope I haven't missed anyone :giggle: )
@melissa-bee, @Pompous Blue, @Beamodel, @greenandchic, @PJaye, @IDareT'sHair, @all_1_length, @foxxymami, @Cherrypie*, @g.lo
(Sorry I said I would start before, but some extremely important things came up. )

Ladies I've done some research on the Neem plant and it is ANTI ANDROGENIC. Even when taken it was noted to substantially lower testosterone and therefore INCREASE GROWTH for dht and hormone related hair loss issues. Of course that lowers DHT because testosterone is used to make DHT. This was a study for the oral intake.


Effect of aqueous neem (Azadirachta indica) extract on testosterone and other blood constituents in male rats. A pilot study.
http://www.ncbi.nlm.nih.gov/pubmed/7817539

"Effect of oral administration of crude aqueous neem extract on serum testosterone and other blood constituents was studied in the male Wistar rats for 10 weeks. The neem treatment resulted in significant decreases (p < 0.01) in total testosterone, total bilirubin and K+ in serum. There were also increases (p < 0.05) in packed cell volume, mean corpuscular haemoglobin concentration, red blood cell, white blood cell and lymphocyte counts without showing any cytotoxic effects in the body."


Im not sure if I'll intake it orally yet, if I do it will be like 12 hours away from any medication. I would suggest that also. BUT ANYWAY :grin: we CAN use it topically Yipeeee :clap: !!!! TheraNeem is a natural product line that actually carries the product. So I'm starting out with Neem oil, pure. I MIGHT use a small bit of jojoba to carry it as I don't know if it likens to penetrate into the scalp like jojoba is known to do. Here are two different brands but both are 100% neem oil and both I think are at Vitacost and Swanson.



However I do plan to use the caffeine and or tea that two of our users declares by (I don't use swear :) ). I want to try some in an oil to see if it dissolves so to use it as a growth oil. If that doesn't work as well, so what I'll just use it as our poster uses it as it has REALLY worked for her. Oh and here's another study that shows the HAIR GROWTH STIMULATING properties of caffeine on the hair follicles.


Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and TGF-β2-/IGF-1-mediated regulation of hair cycle in male and female human hair follicles in vitro.
http://www.ncbi.nlm.nih.gov/pubmed/24836650

"This study reveals new growth-promoting effects of caffeine on human hair follicles of both genders at different (molecular, cellular and organ) levels."
 
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sugarbaybie

Well-Known Member
Also ladies,

@melissa-bee, @Pompous Blue, @Beamodel, @greenandchic, @PJaye, @IDareT'sHair, @all_1_length, @foxxymami, @Cherrypie*, @g.lo

I found out that ROSEMARY oil will extend hair growth in people who's growth has been stunted by testosterone exposure (aka dht issues). WOW! I'm thinking of mixing the rosemary with the Neem oil, applying that to my scalp daily, as both are anti androgenic and both should decrease breakage because they are OILS. it beats the heck out of Rogaine which is formulated in alcohol and you ladies know that will dry and break Black hair. But yes, see the Rosemary study below. It's also a dht blocking ingredient in one of the Liquid Gold's hair products.



Topical administration of Rosmarinus officinalis (Rosemary) leaf extract (RO-ext, 2 mg/day/mouse) improved hair regrowth in C57BL/6NCrSlc mice that experienced hair regrowth interruption induced by testosterone treatment.
http://www.ncbi.nlm.nih.gov/pubmed/22517595

"Topical administration of Rosmarinus officinalis leaf extract (RO-ext, 2 mg/day/mouse) improved hair regrowth in C57BL/6NCrSlc mice that experienced hair regrowth interruption induced by testosterone treatment. In addition, RO-ext promoted hair growth in C3H/He mice that had their dorsal areas shaved. To investigate the antiandrogenic activity mechanism of RO-ext, we focused on inhibition of testosterone 5α-reductase, which is well recognized as one of the most effective strategies for the treatment of androgenic alopecia. RO-ext showed inhibitory activity of 82.4% and 94.6% at 200 and 500 µg/mL, respectively. As an active constituent of 5α-reductase inhibition, 12-methoxycarnosic acid was identified with activity-guided fractionation. In addition, the extract of R. officinalis and 12-methoxycarnosic acid inhibited androgen-dependent proliferation of LNCaP cells as 64.5% and 66.7% at 5 µg/mL and 5 μM, respectively. These results suggest that they inhibit the binding of dihydrotestosterone to androgen receptors. Consequently, RO-ext is a promising crude drug for hair growth."

Once again with most pure topicals I'm thinking of adding a liiiittle bit of jojoba oil to help it penetrate into the scalp.
 
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IDareT'sHair

PJ Rehabilitation Center
Right now I'm using (rotating of course):
Pumpkin Seed Oil Pure Cold Pressed
BlueRoze Beauty's Pumpkin Hair Whip & BRB's Pumpkin Puree
Saw Palmetto Tea Rinses (on occasion)
Rosemary Tea Rinses
Coffee Rinses (will start back 06/01
Viviscal Vitamins
Hydratherma Naturals Growth Lotion
Hairitage Hydrations Jar of Joe
other miscellaneous products

*each of the above have claims to have some affect on DHT blockage or removal*

@sugarbaybie
 

sugarbaybie

Well-Known Member
IDareT'sHair Thanks SOOO much! I think I remember you doing a similar list up top. Tell me, how is this working out for you??? OHHH IVE BEEN INTENDING on trying the pumpkin seed oil!!! Please tell me if that is doing something because Im about to do a nice sized order online and if so, I'll include it.
 

IDareT'sHair

PJ Rehabilitation Center
sugarbaybie

I used it before, loved it, ran out and just reupped a week or so ago.:yep:

This time, I'll monitor it more closely.

It's a nice lightweight oil, so I think it would still be worth getting.:lick:

Brown Butter Beauty also has a nice Neem Oil Blend with Walnut Hull etc....that's super nice & smells good and purports to 'block/remove DHT.

I personally like the Tea & Coffee Rinses and the Viviscal.

I'm also using Mega-Tek and M/N (in moderation).

Not for DHT, but for growth.

The only thing I tend to shy away from is Sulfur (because it's so drying).

So, it's very hard to pin-point one particular product, because I'm always using something.:lol: #lifeofapj
 
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melissa-bee

Well-Known Member
I have started using rosemary infused castor oil and hoping that will help for growing back my crown.
Also today i decided that I will get full female hormone screening from a private clinic. I know that I have been having hormone problems for a few years and I actually need to know exactly what to balance before it's too late.
 

sugarbaybie

Well-Known Member
Ladies, UPDATE!

@melissa-bee, @Pompous Blue, @Beamodel, @greenandchic, @PJaye, @IDareT'sHair, @all_1_length, @foxxymami, @Cherrypie*, @g.lo



Pumpkin Seed Oil PROVEN in study to increase hair COUNT (that sounds like REGROWTH) and stimulate hair growth in men with AGA (Androgenic Alopecia/Male or Female Balding/Dht balding)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017725/

"Pumpkin seed oil (PSO) has been shown to block the action of 5-alpha reductase and to have antiandrogenic effects on rats. This randomized, placebo-controlled, double-blind study was designed to investigate the efficacy and tolerability of PSO for treatment of hair growth in male patients with mild to moderate androgenetic alopecia (AGA). 76 male patients with AGA received 400
mg of PSO per day
or a placebo for 24 weeks. Change over time in scalp hair growth was evaluated by four outcomes: assessment of standardized clinical photographs by a blinded investigator; patient self-assessment scores; scalp hair thickness; and scalp hair counts. Reports of adverse events were collected throughout the study. After 24 weeks of treatment, self-rated improvement score and self-rated satisfaction scores in the PSO-treated group were higher than in the placebo group (P = 0.013, 0.003). The PSO-treated group had more hair after treatment than at baseline, compared to the placebo group (P < 0.001). Mean hair count increases of 40% were observed in PSO-treated men at 24 weeks, whereas increases of 10% were observed in placebo-treated men (P < 0.001). Adverse effects were not different in the two groups."





Ladies as I find things that also offers proof in a controlled study, I'll update you on them.






So before I've located proof/studies on:
  • Caffeine (2 studies it causes hair growth, 1 in AGA sufferers)
  • Neem (when taken orally significantly decreases testosterone, seek medical attention before doing so. Also it DOES come in a TOPICAL form)
  • Rosemary Oil (Study shows topically it's anti androgenic in AGA sufferers)
  • (And now) Pumpkin Seed Oil (this study SHOWS at a certain dosage, increase in hair thickness and stimulates growth. There is even a picture BELOW.)
Ladies we can DO THIS! :clap:
 
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Beamodel

Well-Known Member
Ladies, UPDATE! @melissa-bee, @Pompous Blue, @Beamodel, @greenandchic, @PJaye, @IDareT'sHair, @all_1_length, @foxxymami, @Cherrypie*, @g.lo Pumpkin Seed Oil PROVEN in study to increase hair diameter (that sounds like counteracting miniaturization) and stimulate hair growth in men with AGA (Androgenic Alopecia/Male or Female Balding/Dht balding) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017725/ "Pumpkin seed oil (PSO) has been shown to block the action of 5-alpha reductase and to have antiandrogenic effects on rats. This randomized, placebo-controlled, double-blind study was designed to investigate the efficacy and tolerability of PSO for treatment of hair growth in male patients with mild to moderate androgenetic alopecia (AGA). 76 male patients with AGA received 400mg of PSO per day or a placebo for 24 weeks. Change over time in scalp hair growth was evaluated by four outcomes: assessment of standardized clinical photographs by a blinded investigator; patient self-assessment scores; scalp hair thickness; and scalp hair counts. Reports of adverse events were collected throughout the study. After 24 weeks of treatment, self-rated improvement score and self-rated satisfaction scores in the PSO-treated group were higher than in the placebo group (P = 0.013, 0.003). The PSO-treated group had more hair after treatment than at baseline, compared to the placebo group (P < 0.001). Mean hair count increases of 40% were observed in PSO-treated men at 24 weeks, whereas increases of 10% were observed in placebo-treated men (P < 0.001). Adverse effects were not different in the two groups." Ladies as I find things that also offers proof in a controlled study, I'll update you on them. So before I've located proof/studies on: [*]Caffeine (2 studies it causes hair growth, 1 in AGA sufferers) [*]Neem (when taken orally significantly decreases testosterone, seek medical attention before doing so. Also it DOES come in a TOPICAL form) [*]Rosemary Oil (Study shows topically it's anti androgenic in AGA sufferers) [*](And now) Pumpkin Seed Oil (this study SHOWS at a certain dosage, increase in hair diameter/thickness and stimulates growth there is even a picture.) Ladies we can DO THIS! :clap:

sugarbaybie

Thanks for the research. Yes,I'm using pumpkin seed oil and I'm loving it. It's too soon to see if it's helping with anything just yet but none the less, still loving it.

I'm also using green tea and saw palmetto tea rinses too.
 

IDareT'sHair

PJ Rehabilitation Center
sugarbaybie

Thanks for continuing to do the Research on this topic. Very good information.:yep:

I am still using things like:
Pumpkin Seed Oil & Products with Pumpkin Seed
Rosemary based products
Coffee
Tea
Ayurvedic Products
And several growth aides that may support these efforts
 

melissa-bee

Well-Known Member
Thanks for the update sugarbaybie
I heard read that it's good to eat pumpkin seeds to get rid of dht internally as well so have been meaning to include them in my diet.
 

greenandchic

Well-Known Member
sugarbaybie

Thanks for doing the research! I will look into pumpkin seed oil. I assume I would use it topically unless I need to also take it internally.

Sent from my iPhone using LHCF
 

sugarbaybie

Well-Known Member
@sugarbaybie

A cheap solution for me is either Black tea rinses (I use Earl Grey) or add 1/8th tsp pure caffeine (purchased from amazon.com) to my 8 oz. moisturizing deep conditioners. I DC at least once a week. Been doing this since 2010.

I had a distinctive female pattern balding patch in my crown along with slow growth. The patch was the size of my palm. Since I've been doing the above, no more balding; no more slow growth. Glad those days are OVER!

BTW female pattern baldness runs in my family.

Pompous Blue do you have a link to the caffeine powder you use from amazon?
 
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